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Context Info
Confidence 0.16
First Reported 1987
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.53
Pain Relevance 1.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Sst) extracellular region (Sst) plasma membrane (Oprl1)
signal transducer activity (Oprl1)
Sst (Rattus norvegicus)
Oprl1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Somatostatin 15 100.00 Very High Very High Very High
opiate 5 100.00 Very High Very High Very High
Endogenous opioid 2 92.80 High High
antagonist 3 82.00 Quite High
Morphine 3 75.00 Quite High
Cholecystokinin 2 75.00 Quite High
MU agonist 1 75.00 Quite High
analgesia 2 73.76 Quite High
Intracerebroventricular 2 71.84 Quite High
agonist 1 54.64 Quite High
Disease Link Frequency Relevance Heat
Hypothermia 2 95.20 Very High Very High Very High
Fever 4 86.28 High High
Toxicity 2 60.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A series of cyclic conformationally restrained octapeptide analogs of somatostatin were examined for their ability to inhibit the binding of tritiated mu, kappa, and delta opiate receptor ligands.
somatostatin Binding (binding) of delta opiate receptor associated with somatostatin and opiate
1) Confidence 0.16 Published 1987 Journal Peptides Section Abstract Doc Link 2893361 Disease Relevance 0.06 Pain Relevance 0.94
These results indicate that a lower dose of SST (1 microgram) stimulates the mu-receptor (directly or indirectly) and a higher dose (10 micrograms) interacts with the kappa-receptor in regulation of Tb.
SST Binding (interacts) of kappa-receptor associated with somatostatin
2) Confidence 0.08 Published 1997 Journal Brain Res. Section Abstract Doc Link 9037404 Disease Relevance 0.47 Pain Relevance 0.80

General Comments

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