INT315384

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Adcyap1, Casp3) mitochondrion (Casp3) intracellular (Casp3)
cytoplasm (Casp3) peptidase activity (Casp3) extracellular space (Adcyap1)
Anatomy Link Frequency
Pituitary 2
Adcyap1 (Rattus norvegicus)
Casp3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuropeptide 7 99.96 Very High Very High Very High
Inflammation 20 79.52 Quite High
cytokine 14 5.00 Very Low Very Low Very Low
Kinase C 6 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 18 95.88 Very High Very High Very High
Encephalitis 7 79.52 Quite High
Disease 4 75.76 Quite High
Neurological Disease 1 71.92 Quite High
INFLAMMATION 17 70.36 Quite High
Immune System Diseases 1 65.28 Quite High
Neurodegenerative Disease 5 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Brain Disease 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Studies of putative factors for rescue showed that the neuropeptide, Pituitary adenylate cyclase-activating polypeptide (PACAP) increased cell viability, the levels of p-Bad and reduced caspase-3 activation in the NPCs.
Pituitary adenylate cyclase-activating polypeptide Negative_regulation (reduced) of Positive_regulation (activation) of caspase-3 in Pituitary associated with neuropeptide
1) Confidence 0.02 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2885411 Disease Relevance 0.53 Pain Relevance 0.20

General Comments

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