INT3154

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.58
First Reported 1978
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.22
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Cyb5a) mitochondrion (Cyb5a) endoplasmic reticulum (Cyb5a)
enzyme binding (Cyb5a) molecular_function (Cyb5a)
Cyb5a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
halothane 6 99.72 Very High Very High Very High
anesthesia 4 99.32 Very High Very High Very High
cINOD 3 85.68 High High
Potency 1 72.48 Quite High
depression 1 50.00 Quite Low
Paracetamol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 3 85.28 High High
Depression 1 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Microsomal cytochrome P450 and cytochrome b5 decreased after halothane anesthesia (by 7 to 20 per cent of control).
Negative_regulation (decreased) of Microsomal cytochrome P450 associated with anesthesia and halothane
1) Confidence 0.58 Published 1978 Journal Anesthesiology Section Abstract Doc Link 646150 Disease Relevance 0 Pain Relevance 0.32
Microsomal cytochrome P450 and cytochrome b5 decreased after halothane anesthesia (by 7 to 20 per cent of control).
Negative_regulation (decreased) of cytochrome b5 associated with anesthesia and halothane
2) Confidence 0.37 Published 1978 Journal Anesthesiology Section Abstract Doc Link 646150 Disease Relevance 0 Pain Relevance 0.32
Indomethacin in vitro also caused a loss of cytochrome b5, NADH-cytochrome b5 reductase, NADPH-cytochrome c reductase and epoxide hydrolase activities, but an activation of UDP-glucuronyltransferase.
Negative_regulation (loss) of cytochrome b5
3) Confidence 0.29 Published 1986 Journal Biochem. Pharmacol. Section Abstract Doc Link 3778523 Disease Relevance 0.22 Pain Relevance 0.26
Parenteral nutrition decreased microsomal cytochrome P450 concentration (47%), p-nitroanisole demethylase activity (68%) and p-nitrophenol UDP-glucuronosyltransferase activity (58%).
Negative_regulation (decreased) of microsomal cytochrome P450
4) Confidence 0.02 Published 1995 Journal JPEN J Parenter Enteral Nutr Section Body Doc Link 8523630 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox