INT315417

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Context Info
Confidence 0.43
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Prnp) endoplasmic reticulum (Prnp) nucleolus (Prnp)
plasma membrane (Prnp) nucleus (Prnp) cytoplasm (Prnp)
Prnp (Mus musculus)
Pain Link Frequency Relevance Heat
Lasting pain 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
midbrain 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rabies Virus Infection 3 72.16 Quite High
Neurodegenerative Disease 2 68.88 Quite High
Viral Meningitis 2 46.72 Quite Low
Viral Infection 2 44.96 Quite Low
Encephalitis 1 26.88 Quite Low
Prion Diseases 16 5.00 Very Low Very Low Very Low
Disease 10 5.00 Very Low Very Low Very Low
Infection 10 5.00 Very Low Very Low Very Low
Chronic Wasting Disease 6 5.00 Very Low Very Low Very Low
Scrapie 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RT-PCR (figure 1B) and FACS analyses (figure 1C and D) demonstrate that all three shRNA plasmids suppressed PrP mRNA and protein levels, respectively, in a dose-dependent manner, to less than 25% of normal levels (p<0.01, n?
Negative_regulation (suppressed) of Transcription (levels) of PrP
1) Confidence 0.43 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2885418 Disease Relevance 0.14 Pain Relevance 0

General Comments

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