INT31550

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Context Info
Confidence 0.30
First Reported 1987
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 10
Total Number 10
Disease Relevance 1.54
Pain Relevance 2.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lyase activity (Car1) Golgi apparatus (Car1) cytoplasm (Car1)
Anatomy Link Frequency
hippocampus 2
pyramidal cell 1
dentate gyrus 1
neurons 1
brain 1
Car1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Cannabinoid 7 100.00 Very High Very High Very High
Hippocampus 28 99.96 Very High Very High Very High
long-term potentiation 12 99.90 Very High Very High Very High
Pyramidal cell 36 99.12 Very High Very High Very High
ketamine 3 93.28 High High
gABA 2 90.96 High High
Enkephalin 2 90.88 High High
Neurotransmitter 1 89.68 High High
Opioid 5 86.16 High High
Glutamate 9 85.48 High High
Disease Link Frequency Relevance Heat
Convulsion 7 99.84 Very High Very High Very High
Neurodegenerative Disease 4 98.12 Very High Very High Very High
Apoptosis 3 97.36 Very High Very High Very High
Anxiety Disorder 4 96.24 Very High Very High Very High
Infection 56 94.28 High High
Depression 8 81.28 Quite High
Leukemia 2 61.76 Quite High
Genetic Translocation 1 52.80 Quite High
Rabies Virus Infection 12 50.00 Quite Low
Cognitive Disorder 4 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the hippocampus of aged rats, [3H] alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate binding in CA1 and [3H]kainate binding in CA3 were reduced.
CA1 Binding (binding) of in hippocampus associated with hippocampus
1) Confidence 0.30 Published 1996 Journal Neuroscience Section Abstract Doc Link 8884770 Disease Relevance 0 Pain Relevance 0.17
Seven days after the last kindled seizure, delta binding was decreased by 11-17% throughout CA1, CA3, and the dentate gyrus.
CA1 Binding (binding) of in dentate gyrus associated with convulsion
2) Confidence 0.30 Published 1987 Journal Brain Res. Section Abstract Doc Link 3038268 Disease Relevance 0.53 Pain Relevance 0.48
The magnitude of long-term potentiation (LTP) of reactivity of Ca1 to stimulation of CA3 neurons also increased during weeks in culture in parallel with the change in spine density.
Ca1 Binding (reactivity) of in neurons associated with long-term potentiation
3) Confidence 0.29 Published 1997 Journal J. Neurophysiol. Section Abstract Doc Link 9084624 Disease Relevance 0 Pain Relevance 0.39
The present study was designed to evaluate the interactions between cannabinoid and NO systems in the CA1 brain region of the rats using the plus-maze test. 2.
CA1 Neg (NO) Binding (interactions) of in brain associated with cannabinoid
4) Confidence 0.28 Published 2007 Journal Clin. Exp. Pharmacol. Physiol. Section Abstract Doc Link 17250643 Disease Relevance 0.25 Pain Relevance 0.40
Thus local excitation in CA1 does not appear to be asymmetrically arranged in the way suggested for CA3. 6.
CA1 Binding (excitation) of
5) Confidence 0.27 Published 1988 Journal J. Neurophysiol. Section Abstract Doc Link 2893830 Disease Relevance 0 Pain Relevance 0.22
In rats, moderate hypothermic CPB with hemodilution is associated with CA1 hippocampus bax and bcl-2 gene expression and neuronal apoptosis during the early post-CPB recovery period.
CA1 Binding (associated) of in hippocampus associated with hippocampus and neurodegenerative disease
6) Confidence 0.22 Published 2006 Journal Anesth. Analg. Section Abstract Doc Link 16551891 Disease Relevance 0.33 Pain Relevance 0.21
Areas of CA1 stratum radiatum were measured in each section using Scion Image software (Scion Corp., Frederick, MD, USA), and the total volume of CA1 stratum radiatum in each rat was estimated as
CA1 Binding (radiatum) of
7) Confidence 0.21 Published 2005 Journal Environ Health Perspect Section Body Doc Link PMC1257590 Disease Relevance 0 Pain Relevance 0.10
We did observe occasional labelling in CA1 of cells outside the pyramidal cell layer already after 3.5?
CA1 Binding (labelling) of in pyramidal cell associated with pyramidal cell
8) Confidence 0.19 Published 2008 Journal Frontiers in Neuroanatomy Section Body Doc Link PMC2629710 Disease Relevance 0.09 Pain Relevance 0.14
Even in CA1, there were fewer ?
CA1 Binding (were) of
9) Confidence 0.19 Published 2008 Journal Frontiers in Neuroanatomy Section Body Doc Link PMC2629710 Disease Relevance 0.09 Pain Relevance 0.05
We then incubated CA1 hippocampal cell lysates with immobilized anti-PDGF?
CA1 Binding (lysates) of
10) Confidence 0.09 Published 2008 Journal Mol Brain Section Body Doc Link PMC2651131 Disease Relevance 0.25 Pain Relevance 0.08

General Comments

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