INT315532

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NFS1, ISCU) mitochondrion (NFS1, ISCU) nucleus (NFS1, ISCU)
cytoplasm (NFS1, ISCU) small molecule metabolic process (NFS1) protein complex assembly (NFS1)
NFS1 (Homo sapiens)
ISCU (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Iron Overload 24 70.28 Quite High
Disease 27 62.80 Quite High
Disease Progression 1 54.32 Quite High
Anaemia 18 21.40 Low Low
Ataxia 24 10.40 Low Low
Sideroblastic Anemia 15 5.00 Very Low Very Low Very Low
Muscle Disease 9 5.00 Very Low Very Low Very Low
Porphyria 5 5.00 Very Low Very Low Very Low
Syndrome 5 5.00 Very Low Very Low Very Low
Erythropoietic Protoporphyria 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
S cluster biogenesis in eukaryotes was undermined by the discovery that isoforms of the cysteine desulfurase, ISCS, the scaffold, ISCU, and the alternative scaffold, NFU, not only were present in the cytosol but also were shown to be important for cytosolic Fe?
cysteine desulfurase Binding (scaffold) of ISCU
1) Confidence 0.19 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.37 Pain Relevance 0

General Comments

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