INT315535

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Context Info
Confidence 0.28
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.70
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ABCB7, FECH) generation of precursor metabolites and energy (FECH) transport (ABCB7)
small molecule metabolic process (FECH) ATPase activity (ABCB7) transmembrane transport (ABCB7)
ABCB7 (Homo sapiens)
FECH (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hematological Disease 1 99.46 Very High Very High Very High
Anaemia 18 97.84 Very High Very High Very High
Sideroblastic Anemia 15 96.04 Very High Very High Very High
Targeted Disruption 2 81.12 Quite High
Iron Overload 24 73.80 Quite High
Ataxia 24 64.40 Quite High
Disease 27 50.00 Quite Low
Porphyria 5 45.68 Quite Low
Muscle Disease 9 5.00 Very Low Very Low Very Low
Syndrome 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Human ABCB7 has an additional role in heme synthesis and hematopoiesis as revealed by a putative interaction between ABCB7 and FECH which has been demonstrated in pull-down assays, and anemia caused by ABCB7 depletion (83,84).
ABCB7 Binding (interaction) of FECH associated with hematological disease and anaemia
1) Confidence 0.28 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.70 Pain Relevance 0

General Comments

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