INT315588

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.57
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ACO1) mitochondrion (ACO1) lyase activity (ACO1)
Golgi apparatus (ACO1) endoplasmic reticulum (ACO1) RNA binding (ACO1)
ACO1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 4 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Iron Overload 48 91.84 High High
Anaemia 36 89.60 High High
Disease 54 86.00 High High
Genomic Instability 4 79.56 Quite High
Parkinson's Disease 2 72.60 Quite High
Ataxia 48 48.04 Quite Low
Sideroblastic Anemia 30 47.60 Quite Low
Muscle Disease 18 37.40 Quite Low
Disease Progression 2 24.08 Low Low
Retina Disease 2 23.96 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
S cluster biogenesis is therefore important for the IRP1-mediated regulation of human iron homeostasis.


Regulation (regulation) of IRP1
1) Confidence 0.18 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.07 Pain Relevance 0
S cluster biogenesis in the regulation of the cytosolic regulatory protein, IRP1.


Regulation (regulation) of IRP1
2) Confidence 0.18 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.49 Pain Relevance 0

General Comments

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