INT315614

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Context Info
Confidence 0.25
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.82
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (FXN) mitochondrion (FXN) mitochondrion organization (FXN)
enzyme binding (FXN) cytoplasm (FXN)
FXN (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 27 92.00 High High
Ataxia 24 81.96 Quite High
Anaemia 18 77.16 Quite High
Iron Overload 24 74.12 Quite High
Coronary Heart Disease 1 59.28 Quite High
Hypertrophic Cardiomyopathy 1 58.92 Quite High
Dysarthria 1 54.52 Quite High
Neurodegenerative Disease 1 42.36 Quite Low
Sideroblastic Anemia 15 36.96 Quite Low
Porphyria 5 29.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expansion of the GAA repeat has been proposed to lead to gene silencing by allowing heterochromatin formation to silence transcription (55) or to inhibit transcription of the frataxin gene by facilitating formation of a persistent DNA?
Negative_regulation (inhibit) of Transcription (transcription) of frataxin gene
1) Confidence 0.25 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.82 Pain Relevance 0

General Comments

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