INT315621

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.34
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 11
Disease Relevance 4.11
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

chromosome segregation (CIAO1)
CIAO1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 22 14.92 Low Low
Glutamate 11 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anaemia 198 100.00 Very High Very High Very High
Iron Overload 264 99.90 Very High Very High Very High
Disease 297 99.16 Very High Very High Very High
Stress 44 96.96 Very High Very High Very High
Ataxia 264 95.44 Very High Very High Very High
Porphyria 55 89.20 High High
Sideroblastic Anemia 165 85.28 High High
Protein Deficiency 11 65.88 Quite High
Repression 22 60.08 Quite High
Muscle Disease 99 47.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The ATPase proteins, Nar1 and Cia1, may function in cytosolic cluster transfer (12,22), and a newly identified protein, Dre2 (23), may also contribute to cytosolic Fe?
Gene_expression (The) of Cia1
1) Confidence 0.34 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0 Pain Relevance 0
The ATPase proteins, Nar1 and Cia1, may function in cytosolic cluster transfer (12,22), and a newly identified protein, Dre2 (23), may also contribute to cytosolic Fe?
Gene_expression (function) of Cia1
2) Confidence 0.34 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0 Pain Relevance 0
sulfur cluster biogenesis is accompanied by cytosolic iron depletion, which may result in part from the fact that mitochondrial iron uptake occurs at the expense of cytosolic iron.
Gene_expression (depletion) of cytosolic iron
3) Confidence 0.29 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.80 Pain Relevance 0
The fact that cytosolic iron depletion occurs in conjunction with mitochondrial iron overload may explain why cytosolic iron?
Gene_expression (depletion) of cytosolic iron associated with iron overload
4) Confidence 0.29 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.79 Pain Relevance 0
sulfur cluster biogenesis in three human diseases, and the problems that are engendered in mitochondrial and cytosolic iron homeostasis, we suggest that the next frontier will consist of molecular characterization of a molecule synthesized in mitochondria that is exported to the cytosolic/nuclear compartment, perhaps by ABCB7, and which represents a gauge of mitochondrial iron status by possessing or depending on an iron?
Gene_expression (mitochondrial) of cytosolic iron associated with disease
5) Confidence 0.29 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.15 Pain Relevance 0
In particular, the iron exporter gene ferroportin (FPN1) is significantly upregulated, potentially exacerbating the cytosolic iron deficiency.
Gene_expression (deficiency) of cytosolic iron associated with anaemia
6) Confidence 0.29 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.45 Pain Relevance 0
Just as mammalian cytosolic iron homeostasis is regulated in part by a cytosolic iron?
Gene_expression (homeostasis) of cytosolic iron
7) Confidence 0.29 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.17 Pain Relevance 0
sulfur cluster biogenesis is accompanied by cytosolic iron depletion, which may result in part from the fact that mitochondrial iron uptake occurs at the expense of cytosolic iron.
Gene_expression (expense) of cytosolic iron
8) Confidence 0.29 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.81 Pain Relevance 0
If levels of this putative signaling molecule decrease, the cell imports more iron from the cytosol into mitochondria, resulting in mitochondrial iron overload and cytosolic iron deficiency, which slows cytosolic Fe?
Gene_expression (deficiency) of cytosolic iron associated with anaemia and iron overload
9) Confidence 0.29 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.44 Pain Relevance 0
The cytosolic iron sensors IRP1, which senses iron levels through an iron?
Gene_expression (sensors) of cytosolic iron
10) Confidence 0.29 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.34 Pain Relevance 0
sulfur cluster biogenesis in three human diseases, and the problems that are engendered in mitochondrial and cytosolic iron homeostasis, we suggest that the next frontier will consist of molecular characterization of a molecule synthesized in mitochondria that is exported to the cytosolic/nuclear compartment, perhaps by ABCB7, and which represents a gauge of mitochondrial iron status by possessing or depending on an iron?
Gene_expression (homeostasis) of cytosolic iron associated with disease
11) Confidence 0.29 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.15 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox