INT315632

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.40
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IREB2) mitochondrion (IREB2) RNA binding (IREB2)
cytoplasm (IREB2)
IREB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 7.24 Low Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Iron Overload 24 94.52 High High
Disease 27 87.04 High High
Ataxia 24 69.92 Quite High
Muscle Disease 9 58.56 Quite High
Anaemia 18 48.00 Quite Low
Friedreich Ataxia 2 46.08 Quite Low
Sideroblastic Anemia 15 15.68 Low Low
Erythropoietic Protoporphyria 4 14.44 Low Low
Sunburn 1 8.12 Low Low
Porphyria 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
sulfur cluster, and IRP2, which senses iron levels through iron-dependent degradation by the hemerythrin-like ubiquitin ligase, FBXL5 (99?
Positive_regulation (dependent) of Protein_catabolism (degradation) of IRP2
1) Confidence 0.22 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.40 Pain Relevance 0

General Comments

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