INT315637

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Context Info
Confidence 0.40
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.44
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (FXN) mitochondrion (FXN) mitochondrion organization (FXN)
enzyme binding (FXN) cytoplasm (FXN)
FXN (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 4 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ataxia 48 95.96 Very High Very High Very High
Disease 54 94.60 High High
Anaemia 36 76.84 Quite High
Iron Overload 48 73.80 Quite High
Stress 8 61.52 Quite High
Coronary Heart Disease 2 59.28 Quite High
Hypertrophic Cardiomyopathy 2 58.60 Quite High
Dysarthria 2 54.20 Quite High
Neurodegenerative Disease 2 42.04 Quite Low
Porphyria 10 40.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Human frataxin is transcribed into a primary mRNA 1.3 kb in size (41).
Transcription (transcribed) of frataxin
1) Confidence 0.40 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.62 Pain Relevance 0
The expansion of the GAA repeat has been proposed to lead to gene silencing by allowing heterochromatin formation to silence transcription (55) or to inhibit transcription of the frataxin gene by facilitating formation of a persistent DNA?
Transcription (transcription) of frataxin gene
2) Confidence 0.40 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.82 Pain Relevance 0

General Comments

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