INT31576

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Context Info
Confidence 0.69
First Reported 1988
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 0.89
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SST) extracellular region (SST) cell-cell signaling (SST)
SST (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatostatin 16 100.00 Very High Very High Very High
abdominal pain 5 83.76 Quite High
imagery 28 76.44 Quite High
metalloproteinase 1 68.68 Quite High
palliative 1 62.88 Quite High
Bioavailability 1 57.20 Quite High
agonist 4 50.00 Quite Low
positron emission tomography 7 36.88 Quite Low
Catecholamine 1 6.40 Low Low
Serotonin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 61 99.20 Very High Very High Very High
Pancreatic Cancer 3 98.88 Very High Very High Very High
Disease 8 89.52 High High
Abdominal Pain 5 83.76 Quite High
Diarrhoea 6 82.24 Quite High
Gastrinoma 10 70.28 Quite High
Gastroesophageal Reflux Disease 2 60.20 Quite High
Syndrome 13 59.76 Quite High
Neuroendocrine Cancer 13 50.00 Quite Low
Pituitary Cancer 39 41.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Somatostatin and octreotide: literature review and description of therapeutic activity in pancreatic neoplasia.
Transcription (description) of Somatostatin associated with pancreatic cancer and somatostatin
1) Confidence 0.69 Published 1988 Journal Drug Intell Clin Pharm Section Title Doc Link 2894968 Disease Relevance 0.31 Pain Relevance 0.15
Immunohistochemistry was used to detect adiponectin, beta3-AR, SST, SST2 receptors, tyrosine hydroxylase (TH), and protein gene product 9.5.
Transcription (detect) of SST
2) Confidence 0.68 Published 2010 Journal Gastroenterology Section Body Doc Link 19786030 Disease Relevance 0 Pain Relevance 0
Immunohistochemistry was used to detect adiponectin, beta3-AR, SST, SST2 receptors, tyrosine hydroxylase (TH), and protein gene product 9.5.
Transcription (detect) of SST2
3) Confidence 0.30 Published 2010 Journal Gastroenterology Section Body Doc Link 19786030 Disease Relevance 0 Pain Relevance 0
The GH-lowering effect of SSA is positively correlated with the level of sst2 mRNA expression [27-29].
Transcription (expression) of sst2
4) Confidence 0.15 Published 2010 Journal Diagn Pathol Section Body Doc Link PMC3017030 Disease Relevance 0.09 Pain Relevance 0.15
Octreotide has high affinity for somatostatin receptors, especially subtype 2, resulting in good correlation between scintigraphic findings and the expression of somatostatin receptors on these tumors as determined by immunostaining.
Transcription (expression) of somatostatin associated with cancer and somatostatin
5) Confidence 0.05 Published 2007 Journal Pediatr Radiol Section Body Doc Link PMC2292492 Disease Relevance 0.49 Pain Relevance 0.38

General Comments

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