INT315841

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Context Info
Confidence 0.12
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.29
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Btk) cytosol (Btk) plasma membrane (Btk)
nucleus (Btk) kinase activity (Btk) cytoplasm (Btk)
Btk (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 7 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperplasia 4 88.08 High High
Solid Tumor 1 69.52 Quite High
Myeloid Leukemia 85 60.52 Quite High
Leukemia 15 50.00 Quite Low
Cancer 6 46.84 Quite Low
Blast Crisis 4 12.36 Low Low
Recurrence 6 9.24 Low Low
Pleural Effusion 18 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low
Toxicity 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
and Kit at nanomolar to sub-nanomolar concentrations (Table 1).11 Recently, dasatinib was also shown to bind to other tyrosine and serine/threonine kinases, such as the TEC family kinases, BTK and TEC, the mitogen-activated protein kinases, the receptor tyrosine kinase, discoidin domain receptor 1 and the ephrin receptors.12
Protein_catabolism (protein) of BTK
1) Confidence 0.12 Published 2009 Journal OncoTargets and therapy Section Body Doc Link PMC2886328 Disease Relevance 0.29 Pain Relevance 0

General Comments

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