INT315848

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Context Info
Confidence 0.20
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Abl1) DNA binding (Abl1) cytoplasm (Abl1)
cytosol (Abl1) nucleolus (Abl1) cell adhesion (Abl1)
Abl1 (Mus musculus)
Pain Link Frequency Relevance Heat
Potency 4 95.44 Very High Very High Very High
rheumatoid arthritis 1 30.80 Quite Low
cytokine 1 15.92 Low Low
Central nervous system 7 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fever 3 83.64 Quite High
Colitis 1 82.84 Quite High
Cytomegalovirus Infection 1 81.96 Quite High
Pneumonia 1 81.76 Quite High
Pleural Effusion 18 81.24 Quite High
Lymphocytosis 2 77.08 Quite High
Systemic Lupus Erythematosus 1 54.12 Quite High
Leukemia 15 50.00 Quite Low
Pressure And Volume Under Development 5 49.80 Quite Low
Arthralgia 1 48.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These include upregulation of the ABCB1 or ABCG2 drug efflux pumps,58,63,64 downregulation of human organic cation transporter 1 (hOCT1) drug influx transporters,65,66 overexpression of Lyn, a Src-family kinase,67 and other Bcr-Abl-independent mechanisms.
Positive_regulation (upregulation) of Negative_regulation (downregulation) of Abl
1) Confidence 0.20 Published 2009 Journal OncoTargets and therapy Section Body Doc Link PMC2886328 Disease Relevance 0.61 Pain Relevance 0.05

General Comments

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