INT315867

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.39
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Vhl, VEGFA) mitochondrion (Vhl) extracellular matrix organization (Vhl)
cytosol (Vhl) extracellular space (VEGFA) growth (VEGFA)
Anatomy Link Frequency
platelet 2
Vhl (Rattus norvegicus)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 2 34.72 Quite Low
pain flank 1 29.52 Quite Low
cva 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
nud 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Antiemetics 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
antidepressant 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 3 100.00 Very High Very High Very High
Cancer 8 96.52 Very High Very High Very High
Renal Cancer 34 91.40 High High
Syndrome 12 54.16 Quite High
Cv Unclassified Under Development 15 53.04 Quite High
Nicotine Addiction 1 52.32 Quite High
Obesity 1 51.96 Quite High
Cyst 1 50.48 Quite High
Polycystic Kidney Disease 1 50.20 Quite High
Hematuria 1 30.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Without VHL, in the presence of uninhibited hypoxia-inducible factor, the cascade of intranuclear events leads to transcription of a number of genes, including vascular endothelium growth factor (VEGF) and platelet-derived growth factor (PDGF), leading to increased growth and vascular angiogenesis.8
VHL Positive_regulation (leads) of Transcription (transcription) of VEGF in platelet associated with hypoxia
1) Confidence 0.01 Published 2009 Journal OncoTargets and therapy Section Body Doc Link PMC2886329 Disease Relevance 1.39 Pain Relevance 0

General Comments

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