INT315900

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.65
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (ADAMTS13) extracellular space (ADAMTS13) extracellular region (ADAMTS13)
proteinaceous extracellular matrix (ADAMTS13)
ADAMTS13 (Homo sapiens)
Pain Link Frequency Relevance Heat
peripheral neuropathy 3 89.20 High High
corticosteroid 2 68.32 Quite High
Antihistamine 4 66.72 Quite High
Inflammation 1 29.08 Quite Low
induced neuropathy 2 5.00 Very Low Very Low Very Low
Parenteral administration 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Demyelination 1 5.00 Very Low Very Low Very Low
Root ganglion neuron 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 27 98.02 Very High Very High Very High
Toxicity 20 97.34 Very High Very High Very High
Neutropenia 23 92.16 High High
Peripheral Neuropathy 5 89.20 High High
Neuropathic Pain 17 84.56 Quite High
Fever 7 83.12 Quite High
Thrombocytopenia 2 82.32 Quite High
Disease 14 80.40 Quite High
Fatigue 6 65.00 Quite High
Anaemia 2 64.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Clinical studies have shown that nab-paclitaxel has substantial activity and manageable toxicity as chemotherapy for breast cancer, and the outcome is better than with paclitaxel formulated with CrEL, with almost double the ORR, increased TTP and increased survival in second-line patients.
Positive_regulation (increased) of TTP associated with toxicity and breast cancer
1) Confidence 0.02 Published 2009 Journal OncoTargets and therapy Section Body Doc Link PMC2886338 Disease Relevance 1.65 Pain Relevance 0.11

General Comments

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