INT316

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Context Info
Confidence 0.00
First Reported 1976
Last Reported 2010
Negated 25
Speculated 6
Reported most in Abstract
Documents 105
Total Number 111
Disease Relevance 27.21
Pain Relevance 35.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Cebpz)
Anatomy Link Frequency
blood 26
brain 8
neuronal 3
cortex 2
ventricle 1
Cebpz (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 121 100.00 Very High Very High Very High
narcan 53 100.00 Very High Very High Very High
depression 43 100.00 Very High Very High Very High
cerebral cortex 24 100.00 Very High Very High Very High
tetrodotoxin 16 100.00 Very High Very High Very High
spinal-cord stimulation 12 100.00 Very High Very High Very High
Spinal cord 4 99.98 Very High Very High Very High
cva 47 99.88 Very High Very High Very High
Codeine 20 99.88 Very High Very High Very High
Morphine 38 99.84 Very High Very High Very High
Disease Link Frequency Relevance Heat
Sepsis 60 100.00 Very High Very High Very High
Depression 43 100.00 Very High Very High Very High
Stress 26 100.00 Very High Very High Very High
Hypothermia 25 99.96 Very High Very High Very High
Cv General 3 Under Development 15 99.88 Very High Very High Very High
Increased Venous Pressure Under Development 67 99.84 Very High Very High Very High
Hyperoxia 5 99.84 Very High Very High Very High
Cv General 4 Under Development 52 99.76 Very High Very High Very High
Pressure Volume 2 Under Development 36 99.46 Very High Very High Very High
Hypercapnia 21 99.32 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In 12 cases of the isoflurane group, no apparent rCBF and ECoG changes were seen, except a case with decreased rCBF and slow waves.
Neg (no) Regulation (changes) of rCBF associated with isoflurane
1) Confidence 0.00 Published 2010 Journal J Clin Neurophysiol Section Abstract Doc Link 20505374 Disease Relevance 0 Pain Relevance 0.42
The aims of this study are (1) to assess the effects of volatile anesthetics on regional cerebral blood flow (rCBF) and electrocorticography (ECoG), and (2) to investigate the relationship between rCBF and ECoG influenced by volatile anesthetics.
Regulation (effects) of rCBF in blood
2) Confidence 0.00 Published 2010 Journal J Clin Neurophysiol Section Abstract Doc Link 20505374 Disease Relevance 0 Pain Relevance 0.14
During sevoflurane and isoflurane anesthesia <2.5 minimum alveolar anesthetic concentration, rCBF is affected by ECoG activities rather than pharmacologic action of inhalational anesthetics.
Regulation (affected) of rCBF associated with anesthesia and isoflurane
3) Confidence 0.00 Published 2010 Journal J Clin Neurophysiol Section Abstract Doc Link 20505374 Disease Relevance 0 Pain Relevance 0.44
Four of the nine cases (44.4%) of the sevoflurane group showed no change both in rCBF and ECoG.
Neg (no) Regulation (change) of rCBF
4) Confidence 0.00 Published 2010 Journal J Clin Neurophysiol Section Abstract Doc Link 20505374 Disease Relevance 0 Pain Relevance 0.36
Ergotamine shifted the lower blood pressure limit of CBF autoregulation towards higher blood pressures from 60 +/- 3 mmHg to 82 +/- 4 mmHg (p<0.01), but did not significantly affect the upper blood pressure limit of CBF autoregulation.
Regulation (autoregulation) of CBF in blood associated with ergotamine
5) Confidence 0.61 Published 1998 Journal Cephalalgia Section Abstract Doc Link 9731933 Disease Relevance 0.14 Pain Relevance 0.78
These results indicate that CBF autoregulation was intact during 1 MAC sevoflurane.
Regulation (autoregulation) of CBF
6) Confidence 0.61 Published 1998 Journal Anesth. Analg. Section Abstract Doc Link 9768782 Disease Relevance 0.26 Pain Relevance 0.23
Isoflurane anesthesia was used here to study CBF regulation during repetitive scanning in rats.
Regulation (regulation) of CBF associated with anesthesia and isoflurane
7) Confidence 0.54 Published 2008 Journal NMR Biomed Section Abstract Doc Link 18275045 Disease Relevance 0.36 Pain Relevance 0.28
The impact of PFCs on cerebral function is still under investigation, including its effects on cerebral blood flow (CBF).
Regulation (effects) of CBF in blood
8) Confidence 0.45 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2291566 Disease Relevance 0 Pain Relevance 0
The authors examined the effect of functional ablation of the left cerebral cortex by cortical spreading depression (CSD) or topical application of tetrodotoxin on single cell spiking activity, baseline CBF, and neurovascular coupling in the right rat sensory cortex.
Spec (examined) Regulation (effect) of CBF in cortex associated with tetrodotoxin, depression and cerebral cortex
9) Confidence 0.39 Published 2004 Journal J. Cereb. Blood Flow Metab. Section Abstract Doc Link 15241179 Disease Relevance 0.53 Pain Relevance 0.66
Baseline CBF in the right cortex was unaffected by a left-sided CSD, but decreased by 12% for left cortical application of tetrodotoxin.
Neg (unaffected) Regulation (unaffected) of CBF in cortex associated with tetrodotoxin and depression
10) Confidence 0.39 Published 2004 Journal J. Cereb. Blood Flow Metab. Section Abstract Doc Link 15241179 Disease Relevance 0.59 Pain Relevance 0.83
The results obtained showed that the calculated CMRO2 dynamics lagged changes in CBF by 2.2?
Regulation (changes) of CBF
11) Confidence 0.36 Published 2010 Journal Frontiers in Neuroenergetics Section Body Doc Link PMC2899518 Disease Relevance 0 Pain Relevance 0.07
This oxygen gradient along the arterial vasculature allows the mechanisms regulating CBF to also regulate the delivery of oxygen to sub-serving areas.
Regulation (regulating) of CBF in vasculature
12) Confidence 0.36 Published 2010 Journal Frontiers in Neuroenergetics Section Body Doc Link PMC2899518 Disease Relevance 0 Pain Relevance 0.06
CBF autoregulation was preserved after both ergotamine and sumatriptan.
Regulation (autoregulation) of CBF associated with sumatriptan and ergotamine
13) Confidence 0.27 Published 1998 Journal Cephalalgia Section Abstract Doc Link 9731933 Disease Relevance 0.15 Pain Relevance 0.84
In contrast, CBF autoregulation was impaired with 2 MAC sevoflurane.
Regulation (autoregulation) of CBF
14) Confidence 0.27 Published 1998 Journal Anesth. Analg. Section Abstract Doc Link 9768782 Disease Relevance 0.26 Pain Relevance 0.22
Hypothermia in anesthetized and in ischemic-anesthetized rats did not significantly affect the levels of mitochondrial NADH, CBF and extracellular K(+).
Neg (not) Regulation (affect) of CBF associated with hypothermia
15) Confidence 0.27 Published 2002 Journal Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. Section Abstract Doc Link 12062215 Disease Relevance 0.72 Pain Relevance 0.14
The present findings suggest that central, periventricular beta-endorphinergic mechanisms might play a major role in CBF autoregulation.
Regulation (autoregulation) of CBF
16) Confidence 0.25 Published 1986 Journal Brain Res. Section Abstract Doc Link 2877714 Disease Relevance 0.07 Pain Relevance 0.43
The resting values of CBF and CMRO2 for alpha-chloralose anesthetized rats were 0.40 +/- 0.09 mL x g(-1) x min(-1) and 1.51 +/- 0.06 micromol x g(-1) x min(-1), respectively.
Regulation (values) of CBF
17) Confidence 0.24 Published 2000 Journal J. Cereb. Blood Flow Metab. Section Abstract Doc Link 10724113 Disease Relevance 0 Pain Relevance 0.48
Incremental changes in CBF and CMRO2, when expressed as a percentage change for "deactivation" and "activation" from the respective control conditions, were linear (R2 = 0.997) over the entire range examined with the global and local perturbations.
Spec (examined) Regulation (changes) of CBF
18) Confidence 0.24 Published 2000 Journal J. Cereb. Blood Flow Metab. Section Abstract Doc Link 10724113 Disease Relevance 0 Pain Relevance 0.40
The CBF response in spinalized rats was not affected by cutting cervical sympathetic and facial parasympathetic nerves, while it was almost abolished by intravenous administration of muscarinic and nicotinic cholinergic blocking agents.
Neg (not) Regulation (affected) of CBF in parasympathetic nerves
19) Confidence 0.24 Published 2003 Journal Am. J. Chin. Med. Section Abstract Doc Link 14587883 Disease Relevance 0 Pain Relevance 0.05
The CBF response was abolished by crushing the brachial plexus ipsilateral to the stimulated side.
Regulation (response) of CBF in brachial plexus
20) Confidence 0.24 Published 2003 Journal Am. J. Chin. Med. Section Abstract Doc Link 14587883 Disease Relevance 0 Pain Relevance 0.10

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