INT316039

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.01
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Tauph (Mus musculus)
Pain Link Frequency Relevance Heat
Eae 15 100.00 Very High Very High Very High
long-term potentiation 2 84.56 Quite High
Inflammation 43 59.04 Quite High
Hippocampus 14 37.68 Quite Low
cerebral cortex 5 36.48 Quite Low
cINOD 38 5.00 Very Low Very Low Very Low
Inflammatory response 14 5.00 Very Low Very Low Very Low
cytokine 9 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
Pyramidal cell 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuroblastoma 2 98.98 Very High Very High Very High
Urological Neuroanatomy 1 93.76 High High
Alzheimer's Dementia 21 90.08 High High
Dementia 20 89.60 High High
Toxicity 10 89.44 High High
Disease 169 88.88 High High
Targeted Disruption 64 84.40 Quite High
Frontotemporal Dementia 10 84.32 Quite High
Parkinson's Disease 4 69.68 Quite High
Encephalitis 1 59.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Experiments with differentiated SHSY5Y human neuroblastoma cells indicate that both compounds are capable of reducing the level of tau phosphorylation via inactivation of GSK3-?
Negative_regulation (reducing) of tau phosphorylation associated with neuroblastoma and eae
1) Confidence 0.42 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2915753 Disease Relevance 0.73 Pain Relevance 0.09
Consistent with a role of PS on tau phosphorylation, overexpression of mutant PS1 in mice results in activation of GSK-3?
Negative_regulation (role) of tau phosphorylation associated with eae
2) Confidence 0.41 Published 2010 Journal Frontiers in Aging Neuroscience Section Body Doc Link PMC2887037 Disease Relevance 1.28 Pain Relevance 0.17

General Comments

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