INT316045

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.58
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Psen1) Golgi apparatus (Psen1) endoplasmic reticulum (Psen1)
intracellular (Psen1) embryo development (Psen1) protein complex (Psen1)
Psen1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 43 99.32 Very High Very High Very High
Inflammatory response 14 72.72 Quite High
cINOD 36 66.72 Quite High
cytokine 9 5.00 Very Low Very Low Very Low
Hippocampus 6 5.00 Very Low Very Low Very Low
Eae 3 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
glial activation 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 60 99.32 Very High Very High Very High
Dementia 14 97.92 Very High Very High Very High
Frontotemporal Dementia 8 97.12 Very High Very High Very High
Disease Progression 2 96.40 Very High Very High Very High
Parkinson's Disease 2 95.44 Very High Very High Very High
Disease 81 95.12 Very High Very High Very High
Targeted Disruption 18 87.56 High High
Alzheimer's Dementia 9 76.44 Quite High
Cognitive Disorder 13 64.00 Quite High
Gliosis 3 44.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, a number of loss of function mutations in presenilin-1 have been recently associated to non-Alzheimer's dementias including frontotemporal dementia and dementia with Lewy bodies.
Negative_regulation (number) of Negative_regulation (loss) of presenilin associated with parkinson's disease, dementia and frontotemporal dementia
1) Confidence 0.42 Published 2010 Journal Frontiers in Aging Neuroscience Section Abstract Doc Link PMC2887037 Disease Relevance 1.58 Pain Relevance 0.27

General Comments

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