INT316046

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Context Info
Confidence 0.47
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.57
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell morphogenesis (Ephb2) kinase activity (Ephb2)
Anatomy Link Frequency
Notch 1
Ephb2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 14 83.76 Quite High
Inflammation 43 79.40 Quite High
cINOD 36 62.60 Quite High
cytokine 9 5.00 Very Low Very Low Very Low
Hippocampus 6 5.00 Very Low Very Low Very Low
Eae 3 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
glial activation 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 81 89.92 High High
Brain Disease 4 84.48 Quite High
INFLAMMATION 60 83.36 Quite High
Alzheimer's Dementia 9 41.92 Quite Low
Targeted Disruption 18 5.00 Very Low Very Low Very Low
Dementia 14 5.00 Very Low Very Low Very Low
Cognitive Disorder 13 5.00 Very Low Very Low Very Low
Amyloid Plaque 11 5.00 Very Low Very Low Very Low
Frontotemporal Dementia 8 5.00 Very Low Very Low Very Low
Hypoxia 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-secretase, an aspartyl protease that mediates the regulated intramembrane cleavage of multiple cell surface signaling proteins including among others APP, Notch receptors, ErbB4, E- and N-cadherins, p75 and EphB2 (Koo and Kopan, 2004).
Gene_expression (receptors) of EphB2 in Notch
1) Confidence 0.47 Published 2010 Journal Frontiers in Aging Neuroscience Section Body Doc Link PMC2887037 Disease Relevance 0.57 Pain Relevance 0.23

General Comments

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