INT316049

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Notch1) Golgi apparatus (Notch1) plasma membrane (Notch1)
nucleus (Notch1) embryo development (Notch1) cytoplasm (Notch1)
Anatomy Link Frequency
Notch 2
Notch1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory response 14 96.24 Very High Very High Very High
Inflammation 43 79.12 Quite High
cINOD 36 61.80 Quite High
cytokine 9 5.00 Very Low Very Low Very Low
Hippocampus 6 5.00 Very Low Very Low Very Low
Eae 3 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
glial activation 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 60 95.84 Very High Very High Very High
Cognitive Disorder 13 91.28 High High
Disease 81 76.20 Quite High
Ovarian Cancer 1 72.72 Quite High
Breast Cancer 1 71.80 Quite High
Leukemia 1 71.20 Quite High
Cancer 2 67.64 Quite High
Targeted Disruption 18 58.64 Quite High
Frontotemporal Dementia 8 31.08 Quite Low
Dementia 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
secretase regulates maturation of T cells by regulating the Notch signaling pathway, whereas its inactivation causes side effects on immune function.
Regulation (regulates) of Regulation (regulating) of Notch in Notch
1) Confidence 0.03 Published 2010 Journal Frontiers in Aging Neuroscience Section Body Doc Link PMC2887037 Disease Relevance 0.92 Pain Relevance 0.23

General Comments

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