INT316060

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Erbb4, Ncor2) signal transduction (Erbb4) mitochondrion (Erbb4)
plasma membrane (Erbb4) DNA binding (Ncor2) kinase activity (Erbb4)
Erbb4 (Mus musculus)
Ncor2 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 2 58.60 Quite High
interneuron 1 12.80 Low Low
medulla 1 11.48 Low Low
Hippocampus 6 8.64 Low Low
Pyramidal cell 1 7.88 Low Low
Inflammation 43 5.00 Very Low Very Low Very Low
cINOD 36 5.00 Very Low Very Low Very Low
Inflammatory response 14 5.00 Very Low Very Low Very Low
cytokine 9 5.00 Very Low Very Low Very Low
Eae 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 18 82.96 Quite High
Neurodegenerative Disease 5 75.52 Quite High
Disease 81 66.00 Quite High
Frontotemporal Dementia 8 65.04 Quite High
Nervous System Malformation 1 59.08 Quite High
Hypoxia 5 28.16 Quite Low
Brain Injury 3 27.68 Quite Low
Apoptosis 2 17.60 Low Low
Death 4 16.40 Low Low
INFLAMMATION 60 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-secretase releases the intracellular domain of ErbB4 (Ni et al., 2001), which then binds to TAB2 and the corepressor N-CoR (Sardi et al., 2006).
ErbB4 Binding (binds) of N-CoR
1) Confidence 0.12 Published 2010 Journal Frontiers in Aging Neuroscience Section Body Doc Link PMC2887037 Disease Relevance 0.41 Pain Relevance 0.03

General Comments

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