INT316110

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.16
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (APC, SAE1) protein complex assembly (APC) ligase activity (SAE1)
cytoplasm (APC) cytosol (APC) protein modification process (SAE1)
Anatomy Link Frequency
white matter 1
APC (Homo sapiens)
SAE1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 9 84.40 Quite High
cytokine 2 83.36 Quite High
anesthesia 1 60.88 Quite High
Catecholamine 1 26.16 Quite Low
Electroencephalography 6 5.00 Very Low Very Low Very Low
drug abuse 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Encephalopathy 36 100.00 Very High Very High Very High
Injury 3 99.28 Very High Very High Very High
Periventricular Leukomalacia 1 99.06 Very High Very High Very High
Hypoxia 1 95.32 Very High Very High Very High
Neurodegenerative Disease 2 88.80 High High
INFLAMMATION 10 84.40 Quite High
Sepsis 38 76.92 Quite High
Hematological Disease 1 74.36 Quite High
Apoptosis 6 72.56 Quite High
Critical Illness 1 50.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In a rat model of periventricular leukomalacia, an injury that mimics the pathophysiological findings of SAE, treatment with APC was associated with less endotoxin-induced white matter and myelination deficits.
APC Binding (findings) of SAE in white matter associated with encephalopathy, injury and periventricular leukomalacia
1) Confidence 0.03 Published 2010 Journal Crit Care Section Body Doc Link PMC2887172 Disease Relevance 1.16 Pain Relevance 0.20

General Comments

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