INT316121

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.46
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (HLA-DRA) Golgi apparatus (HLA-DRA) endoplasmic reticulum (HLA-DRA)
intracellular (IL10) cell-cell signaling (IL10) response to stress (IL10)
Anatomy Link Frequency
Plasma 2
monocytes 2
IL10 (Homo sapiens)
HLA-DRA (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 8 99.52 Very High Very High Very High
Inflammation 26 93.20 High High
antagonist 8 82.96 Quite High
anesthesia 34 77.76 Quite High
Neurotransmitter 2 47.04 Quite Low
substance P 6 27.52 Quite Low
Enkephalin 6 26.16 Quite Low
Inflammatory response 12 5.00 Very Low Very Low Very Low
cva 6 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 32 93.20 High High
Stress 10 91.28 High High
Systemic Inflammatory Response Syndrome 14 5.00 Very Low Very Low Very Low
Sepsis 14 5.00 Very Low Very Low Very Low
Injury 10 5.00 Very Low Very Low Very Low
Infection 10 5.00 Very Low Very Low Very Low
Pancreatitis 8 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 6 5.00 Very Low Very Low Very Low
Burns 6 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-10 down-regulated HLA-DR expression on CD14HIGH monocytes, but not on CD14LOW cells (Figure 5).
IL-10 Regulation (regulated) of Gene_expression (expression) of HLA-DR in monocytes
1) Confidence 0.09 Published 2010 Journal Crit Care Section Body Doc Link PMC2887183 Disease Relevance 0.09 Pain Relevance 0.23
Plasma from AAS patients contains not only IL-10 and cortisol, but also other molecules that can differentially modulate the expression of HLA-DR, including cytokines (TNF?
IL-10 Regulation (modulate) of Gene_expression (expression) of HLA-DR in Plasma associated with cytokine
2) Confidence 0.09 Published 2010 Journal Crit Care Section Body Doc Link PMC2887183 Disease Relevance 0.37 Pain Relevance 0.19

General Comments

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