INT316126

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL10, CD14) extracellular region (IL10, CD14) plasma membrane (CD14)
intracellular (IL10) cell-cell signaling (IL10) response to stress (IL10)
Anatomy Link Frequency
monocyte 1
IL10 (Homo sapiens)
CD14 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 4 86.56 High High
Inflammation 13 55.84 Quite High
Inflammatory response 6 16.56 Low Low
anesthesia 17 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Enkephalin 3 5.00 Very Low Very Low Very Low
substance P 3 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 16 55.84 Quite High
Stress 5 53.92 Quite High
Pressure Volume 2 Under Development 2 11.28 Low Low
Systemic Inflammatory Response Syndrome 7 5.00 Very Low Very Low Very Low
Sepsis 7 5.00 Very Low Very Low Very Low
Injury 5 5.00 Very Low Very Low Very Low
Infection 5 5.00 Very Low Very Low Very Low
Pancreatitis 4 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 3 5.00 Very Low Very Low Very Low
Burns 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In agreement with our in vivo observations, we showed that hydrocortisone was able to down-regulate HLA-DR expression on both monocyte subpopulations, whereas IL-10 only acted on CD14HIGH monocytes.
IL-10 Regulation (acted) of CD14HIGH in monocyte
1) Confidence 0.12 Published 2010 Journal Crit Care Section Body Doc Link PMC2887183 Disease Relevance 0.22 Pain Relevance 0.13

General Comments

This test has worked.

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