INT316150

Context Info Confidence 0.43 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 4 Disease Relevance 0.35 Pain Relevance 1.16

extracellular space (CD14) extracellular region (CD14) plasma membrane (CD14)

Anatomy Link Frequency monocytes 8 CD14 (Homo sapiens)

Pain Link Frequency Relevance Heat anesthesia 68 98.24 cytokine 16 87.12 antagonist 16 46.56 Inflammation 52 11.64 Neurotransmitter 4 10.64 Inflammatory response 24 5.00 Enkephalin 12 5.00 substance P 12 5.00 cva 12 5.00 Pain 4 5.00

Disease Link Frequency Relevance Heat Stress 20 87.84 INFLAMMATION 64 11.64 Systemic Inflammatory Response Syndrome 28 5.00 Sepsis 28 5.00 Injury 20 5.00 Infection 20 5.00 Pancreatitis 16 5.00 Cv General 3 Under Development 12 5.00 Burns 12 5.00 Necrosis 8 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Deciphering the acting mediators associated with HLA-DR down-regulation on CD14HIGH and CD14LOW monocytes

Negative_regulation (down) of Regulation (regulation) of CD14LOW in monocytes

1) Confidence 0.43 Published 2010 Journal Crit Care Section Body Doc Link PMC2887183 Disease Relevance 0.09 Pain Relevance 0.29

Deciphering the acting mediators associated with HLA-DR down-regulation on CD14HIGH and CD14LOW monocytes

Negative_regulation (regulation) of Regulation (regulation) of CD14LOW in monocytes

2) Confidence 0.31 Published 2010 Journal Crit Care Section Body Doc Link PMC2887183 Disease Relevance 0.09 Pain Relevance 0.29

Deciphering the acting mediators associated with HLA-DR down-regulation on CD14HIGH and CD14LOW monocytes

Negative_regulation (-) of Regulation (regulation) of CD14LOW in monocytes

3) Confidence 0.31 Published 2010 Journal Crit Care Section Body Doc Link PMC2887183 Disease Relevance 0.09 Pain Relevance 0.29

Deciphering the acting mediators associated with HLA-DR down-regulation on CD14HIGH and CD14LOW monocytes

Negative_regulation (Deciphering) of Regulation (regulation) of CD14HIGH in monocytes

4) Confidence 0.31 Published 2010 Journal Crit Care Section Body Doc Link PMC2887183 Disease Relevance 0.09 Pain Relevance 0.30

General Comments

This test has worked.