INT316369

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.36
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme binding (Atp6ap2)
Anatomy Link Frequency
heart 1
kidney 1
Atp6ap2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 9 88.72 High High
fibrosis 6 68.72 Quite High
chemokine 3 56.40 Quite High
Bioavailability 3 50.60 Quite High
antagonist 15 5.00 Very Low Very Low Very Low
withdrawal 6 5.00 Very Low Very Low Very Low
headache 6 5.00 Very Low Very Low Very Low
beta blocker 3 5.00 Very Low Very Low Very Low
Calcium channel 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Vasculitis 3 88.72 High High
Disease 24 88.40 High High
Stress 3 87.68 High High
Diabetes Mellitus 84 87.04 High High
Fibrosis 9 85.16 High High
Chronic Renal Failure 192 72.68 Quite High
Renal Disease 69 68.68 Quite High
INFLAMMATION 6 59.04 Quite High
Adhesions 3 57.12 Quite High
Cv Unclassified Under Development 54 41.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
More importantly, prorenin, which is normally inactive, becomes catalytically active following binding to this receptor without undergoing proteolysis and thus can contribute to local Ang II formation [29].
prorenin Binding (binding) of
1) Confidence 0.10 Published 2010 Journal Cardiovasc Drugs Ther Section Body Doc Link PMC2887501 Disease Relevance 0.79 Pain Relevance 0.16
This receptor, which is present in many organs including the heart and kidney, binds both renin and prorenin [29].
prorenin Binding (binds) of in heart
2) Confidence 0.10 Published 2010 Journal Cardiovasc Drugs Ther Section Body Doc Link PMC2887501 Disease Relevance 0.78 Pain Relevance 0.19
This receptor, which is present in many organs including the heart and kidney, binds both renin and prorenin [29].
prorenin Binding (binds) of in kidney
3) Confidence 0.03 Published 2010 Journal Cardiovasc Drugs Ther Section Body Doc Link PMC2887501 Disease Relevance 0.78 Pain Relevance 0.19

General Comments

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