INT31643

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Context Info
Confidence 0.59
First Reported 1987
Last Reported 1987
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.62
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (POMC, INS) cell-cell signaling (POMC, INS) extracellular space (POMC, INS)
extracellular region (POMC, INS) carbohydrate metabolic process (INS) cytoplasm (POMC)
Anatomy Link Frequency
plasma 1
POMC (Homo sapiens)
INS (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatostatin 4 99.68 Very High Very High Very High
antagonist 2 99.04 Very High Very High Very High
opiate 2 98.82 Very High Very High Very High
narcan 6 98.46 Very High Very High Very High
Opioid 2 96.64 Very High Very High Very High
Enkephalin 4 89.64 High High
Disease Link Frequency Relevance Heat
Diabetes Mellitus 10 97.92 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present study was aimed at characterizing the effects of beta-endorphin on plasma glucose, insulin and glucagon plasma levels in subjects with type-2 diabetes mellitus.
beta-endorphin Regulation (effects) of insulin in plasma associated with diabetes mellitus
1) Confidence 0.59 Published 1987 Journal Diabete Metab Section Abstract Doc Link 2896134 Disease Relevance 0.25 Pain Relevance 0.15
Naloxone (5 mg), an opiate antagonist, did not produce any significant change in the insulin and glucagon responses to beta-endorphin, while somatostatin (0.25 mg/h) completely abolished the hormonal responses to the opioid.
beta-endorphin Regulation (responses) of insulin associated with antagonist, somatostatin, narcan, opiate and opioid
2) Confidence 0.26 Published 1987 Journal Diabete Metab Section Abstract Doc Link 2896134 Disease Relevance 0.38 Pain Relevance 0.58

General Comments

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