INT316445

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Context Info
Confidence 0.28
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.12
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Il22ra1) cellular_component (Il22ra1) biological_process (Il22ra1)
Anatomy Link Frequency
epithelium 1
Il22ra1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 40 92.84 High High
cytokine 22 13.12 Low Low
Inflammatory response 7 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 47 92.84 High High
Inflammatory Bowel Disease 6 84.84 Quite High
Disease 5 82.72 Quite High
Wound Healing 2 80.64 Quite High
Colitis 9 79.16 Quite High
Cancer 149 58.64 Quite High
Mucositis 2 53.28 Quite High
Targeted Disruption 6 43.96 Quite Low
Adenoma 1 21.00 Low Low
Adenocarcinoma 2 6.64 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sustained activation of Stat3 in (intestinal) epithelium, brought about by activation of the Socs3-unresponsive IL10R, IL22R or gp130Y757F receptors, induces an anti-microbial response.
Positive_regulation (activation) of IL22R in epithelium
1) Confidence 0.28 Published 2010 Journal Cell Div Section Body Doc Link PMC2887830 Disease Relevance 1.12 Pain Relevance 0.16

General Comments

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