INT316482

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cdh1) extracellular space (Il6) extracellular region (Il6)
cell adhesion (Cdh1) Golgi apparatus (Cdh1) plasma membrane (Cdh1)
Il6 (Mus musculus)
Cdh1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 40 78.28 Quite High
chemokine 2 73.40 Quite High
cytokine 22 72.80 Quite High
agonist 1 69.92 Quite High
Inflammatory response 7 47.28 Quite Low
cINOD 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 47 78.28 Quite High
Cancer 149 70.48 Quite High
Apoptosis 11 53.84 Quite High
Stomach Cancer 5 29.36 Quite Low
Gastritis 2 20.60 Low Low
Colitis 9 5.00 Very Low Very Low Very Low
Colon Cancer 6 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 6 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Skin Cancer 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B and Stat3-mediated signaling converge on the EMT process where IL6-mediated Stat3 activation promotes EMT through transcriptional induction of the E-cadherin repressor snail [146], while activation of NF-?
IL6 Positive_regulation (induction) of E-cadherin repressor
1) Confidence 0.03 Published 2010 Journal Cell Div Section Body Doc Link PMC2887830 Disease Relevance 0.33 Pain Relevance 0.15

General Comments

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