INT316488

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Context Info
Confidence 0.29
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.63
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il22, Il10) extracellular region (Il22, Il10) intracellular (Il10)
Anatomy Link Frequency
epithelial cells 1
Il22 (Mus musculus)
Il10 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 40 100.00 Very High Very High Very High
cytokine 22 98.48 Very High Very High Very High
Inflammatory response 7 87.56 High High
cINOD 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 47 100.00 Very High Very High Very High
Colitis 9 99.60 Very High Very High Very High
Targeted Disruption 6 73.12 Quite High
Cancer 149 50.00 Quite Low
Stress 3 15.24 Low Low
Lymphatic System Cancer 1 5.48 Low Low
Apoptosis 11 5.00 Very Low Very Low Very Low
Colon Cancer 6 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 6 5.00 Very Low Very Low Very Low
Skin Cancer 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL22 is expressed during chronic inflammation by Th17, natural killer (NK) and Dendritic (DC) cells [37] and acts on IL-22R subunit expressing (intestinal) epithelial cells to induce IL10 and acute phase protein production [38].
IL22 Positive_regulation (induce) of IL10 in epithelial cells associated with inflammation
1) Confidence 0.29 Published 2010 Journal Cell Div Section Body Doc Link PMC2887830 Disease Relevance 0.63 Pain Relevance 0.32

General Comments

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