INT316511

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Context Info
Confidence 0.28
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 7
Disease Relevance 5.24
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RALBP1) signal transduction (RALBP1) transport (RALBP1)
ATPase activity (RALBP1) intracellular (RALBP1)
Anatomy Link Frequency
penile urethra 2
nerve 1
Bladder 1
RALBP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 12 78.36 Quite High
Spinal cord 16 31.16 Quite Low
COX2 9 5.00 Very Low Very Low Very Low
cINOD 6 5.00 Very Low Very Low Very Low
ketamine 4 5.00 Very Low Very Low Very Low
c fibre 4 5.00 Very Low Very Low Very Low
unmyelinated 4 5.00 Very Low Very Low Very Low
Kinase C 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 129 99.84 Very High Very High Very High
Stress Incontinence 208 99.44 Very High Very High Very High
Stress 3 98.68 Very High Very High Very High
Apoptosis 12 97.24 Very High Very High Very High
Colon Cancer 186 94.72 High High
Metastasis 24 92.12 High High
Recurrence 30 88.56 High High
Breast Cancer 12 86.00 High High
Repression 9 71.92 Quite High
Overactive Bladder 16 69.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression level of RALBP1 was shown to be increased in many cancer cells by expression array analysis.
Gene_expression (expression) of RALBP1 associated with cancer
1) Confidence 0.28 Published 2010 Journal Cancer Informatics Section Body Doc Link PMC2918356 Disease Relevance 1.57 Pain Relevance 0.03
Singhal et al found that antisense RNA for RALBP1 in cancer cell lines or cancer cells in mice suppressed cell growth, and these effects were much more pronounced when combined with other anti-cancer drugs.34
Gene_expression (antisense) of RALBP1 associated with cancer
2) Confidence 0.25 Published 2010 Journal Cancer Informatics Section Body Doc Link PMC2918356 Disease Relevance 1.52 Pain Relevance 0.03
RALBP1, TYMS, RAB12 and RNMT were extracted as Gene Set III-N (N0 vs.
Gene_expression (extracted) of RALBP1
3) Confidence 0.25 Published 2010 Journal Cancer Informatics Section Body Doc Link PMC2918356 Disease Relevance 1.39 Pain Relevance 0.04
For analysis of activation of the lateral branches of the DNP in the penile urethra, the AFs were calculated along 5 lateral DNP branches (Figure 1) in addition to the DNP trunk.
Gene_expression (branches) of DNP in penile urethra associated with stress incontinence
4) Confidence 0.10 Published 2010 Journal BMC Urol Section Body Doc Link PMC2887842 Disease Relevance 0.23 Pain Relevance 0
For analysis of activation of the lateral branches of the DNP in the penile urethra, the AFs were calculated along 5 lateral DNP branches (Figure 1) in addition to the DNP trunk.
Gene_expression (trunk) of DNP in penile urethra associated with stress incontinence
5) Confidence 0.10 Published 2010 Journal BMC Urol Section Body Doc Link PMC2887842 Disease Relevance 0.23 Pain Relevance 0
Bladder responses evoked by IES in the penile and membranous urethra are abolished by bilateral transection of the DNP and CSN, respectively [15], indicating that IES at different intraurethral location allows minimally invasive selective activation of different pudendal afferent branches.
Gene_expression (transection) of DNP in Bladder associated with stress incontinence
6) Confidence 0.10 Published 2010 Journal BMC Urol Section Body Doc Link PMC2887842 Disease Relevance 0.23 Pain Relevance 0
The anatomical courses of the DNP and CSN branches of the pudendal nerve were modeled in Matlab (R2007a, Mathworks) based on previous anatomical data [18-21].
Gene_expression (branches) of DNP in nerve
7) Confidence 0.10 Published 2010 Journal BMC Urol Section Body Doc Link PMC2887842 Disease Relevance 0.08 Pain Relevance 0

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