INT31652

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Context Info
Confidence 0.49
First Reported 1988
Last Reported 1988
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.69
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Tbr1) intracellular (Tbr1) DNA binding (Tbr1)
Anatomy Link Frequency
hypothalamus 1
Tbr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dynorphin 4 99.98 Very High Very High Very High
Kappa opioid receptor 2 98.12 Very High Very High Very High
opioid receptor 1 96.20 Very High Very High Very High
Immobilon 1 87.12 High High
Opioid 1 76.64 Quite High
Disease Link Frequency Relevance Heat
Cancer 6 80.84 Quite High
Anorexia 5 80.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vitro binding assays with 3H-ethylketocyclazocine indicated that dynorphin depletion in the TBR was not sufficient to increase the numbers of kappa opioid receptors in the hypothalamus.
Negative_regulation (depletion) of TBR in hypothalamus associated with dynorphin and kappa opioid receptor
1) Confidence 0.49 Published 1988 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 2896361 Disease Relevance 0.69 Pain Relevance 0.44

General Comments

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