INT316543

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.32
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (GH1, IGF1) extracellular region (GH1, IGF1) signal transduction (IGF1)
Anatomy Link Frequency
plasma 2
GH1 (Homo sapiens)
IGF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 1 60.92 Quite High
headache 4 56.28 Quite High
agonist 42 14.88 Low Low
Onset of action 3 5.52 Low Low
Dopamine 44 5.00 Very Low Very Low Very Low
Somatostatin 32 5.00 Very Low Very Low Very Low
withdrawal 8 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 56 99.86 Very High Very High Very High
Acromegaly 31 99.12 Very High Very High Very High
Recurrence 7 90.96 High High
Heart Failure 2 64.60 Quite High
Pressure And Volume Under Development 6 63.12 Quite High
Diabetes Mellitus 4 62.56 Quite High
Osteoarthritis 1 60.92 Quite High
Prognathism 1 60.28 Quite High
Impaired Glucose Tolerance 2 57.24 Quite High
Headache 4 56.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therapeutic goals in acromegaly are to reduce and/or stabilize tumor size, control plasma GH and IGF-1 levels (fasting GH levels <2.5 ?
GH Regulation (control) of Gene_expression (levels) of IGF-1 in plasma associated with acromegaly and cancer
1) Confidence 0.03 Published 2010 Journal BMC Endocr Disord Section Body Doc Link PMC2887860 Disease Relevance 1.32 Pain Relevance 0.09

General Comments

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