INT316545

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IGF1, SST) extracellular region (IGF1, SST) signal transduction (IGF1)
cell-cell signaling (SST)
Anatomy Link Frequency
hepatocytes 1
IGF1 (Homo sapiens)
SST (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatostatin 32 100.00 Very High Very High Very High
Dopamine 44 91.44 High High
agonist 42 90.72 High High
Onset of action 3 57.76 Quite High
withdrawal 8 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
dopamine receptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adenoma 11 89.32 High High
Acromegaly 31 81.04 Quite High
Pituitary Cancer 20 80.56 Quite High
Cancer 56 78.24 Quite High
Disease 59 62.08 Quite High
Hypopituitarism 3 58.80 Quite High
Prolactinoma 47 50.00 Quite Low
Galactorrhea 10 5.00 Very Low Very Low Very Low
Recurrence 7 5.00 Very Low Very Low Very Low
Acth-secreting Pituitary Adenoma 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
More recently, it has been suggested that a sst ligand may also act peripherally on the GH/IGF-1 axis by binding to somatostatin receptors on peripheral organs, such as hepatocytes in the liver, to inhibit the secretion of IGF-1 [92].
IGF-1 Binding (binding) of somatostatin in hepatocytes associated with somatostatin
1) Confidence 0.06 Published 2010 Journal BMC Endocr Disord Section Body Doc Link PMC2887860 Disease Relevance 0.45 Pain Relevance 0.37

General Comments

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