INT316570

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.95
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

anatomical structure formation involved in morphogenesis (BMP7) extracellular space (BMP7) growth (BMP7)
extracellular region (BMP7)
Anatomy Link Frequency
spinal 2
cartilage 1
BMP7 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 11 75.52 Quite High
Pain 20 5.00 Very Low Very Low Very Low
Osteoarthritis 15 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Perioperative pain 2 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
Oxycodone 2 5.00 Very Low Very Low Very Low
drug abuse 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
visual analogue scale 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 11 96.24 Very High Very High Very High
Osteoporosis 12 93.12 High High
Osteopetrosis 44 76.92 Quite High
Infection 3 67.44 Quite High
Heterotopic Ossification 2 43.36 Quite Low
Hypercalcemia 6 28.00 Quite Low
Stress Fractures 20 17.12 Low Low
Pain 20 5.00 Very Low Very Low Very Low
Osteoarthritis 17 5.00 Very Low Very Low Very Low
Fracture Healing 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Currently, only two BMPs produced using recombinant gene technology have been commercialized: BMP-2 (Infuse®, Medtronic Sofamor, Minneapolis, MN, USA) and BMP-7 (OP-1®, Stryker Biotech, West Chester, PA, USA); and these are limited to approved applications in trauma and spinal fusion [12].
BMP-7 Binding (commercialized) of in spinal associated with injury
1) Confidence 0.37 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2887894 Disease Relevance 0.39 Pain Relevance 0
Currently, only two BMPs produced using recombinant gene technology have been commercialized: BMP-2 (Infuse®, Medtronic Sofamor, Minneapolis, MN, USA) and BMP-7 (OP-1®, Stryker Biotech, West Chester, PA, USA); and these are limited to approved applications in trauma and spinal fusion [12].
OP-1 Binding (commercialized) of in spinal associated with injury
2) Confidence 0.37 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2887894 Disease Relevance 0.39 Pain Relevance 0
It has been shown that BMP-7 also exhibits characteristics as a cartilage anabolic factor because of the ability to induce matrix synthesis and promote repair in cartilage.
BMP-7 Binding (induce) of in cartilage
3) Confidence 0.31 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2920860 Disease Relevance 0.17 Pain Relevance 0.07

General Comments

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