INT316643

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.08
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

growth (Safb) RNA binding (Safb) nucleus (Safb)
DNA binding (Safb)
Anatomy Link Frequency
myotubes 4
Safb (Mus musculus)
Safb - R163C (1)
Pain Link Frequency Relevance Heat
agonist 10 89.44 High High
halothane 4 83.76 Quite High
addiction 22 61.92 Quite High
tetrodotoxin 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Contracture 4 84.60 Quite High
Malignant Hyperthermia 30 50.00 Quite Low
Disease 2 17.48 Low Low
Myelodysplastic Syndromes 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, Ca2+ transients in response to whole cell depolarization were reduced either somewhat in R163C Het myotubes or substantially in R163C Hom myotubes (Fig. 1), which could be at least partially attributed to reduced membrane expression of the DHPR (Fig. 2).
Negative_regulation (reduced) of Gene_expression (myotubes) of Het (R163C) in myotubes
1) Confidence 0.13 Published 2010 Journal The Journal of General Physiology Section Body Doc Link PMC2888063 Disease Relevance 0 Pain Relevance 0
In contrast, the potentiation of L-type currents by ±Bay K 8644 (10 µM) was appreciable in Het myotubes (Fig. 4 B), and even larger in Hom myotubes (Fig. 4 C).
Negative_regulation (appreciable) of Gene_expression (myotubes) of Het in myotubes
2) Confidence 0.11 Published 2010 Journal The Journal of General Physiology Section Body Doc Link PMC2888063 Disease Relevance 0.08 Pain Relevance 0.12

General Comments

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