INT316673

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Context Info
Confidence 0.39
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.89
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (CALR, LRP1) cytoplasm (CALR, LRP1) aging (LRP1)
DNA binding (CALR) protein folding (CALR) extracellular space (CALR)
CALR (Homo sapiens)
LRP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 4 99.90 Very High Very High Very High
Inflammation 32 97.68 Very High Very High Very High
rheumatoid arthritis 110 73.76 Quite High
methotrexate 18 5.00 Very Low Very Low Very Low
visual analogue scale 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 26 99.72 Very High Very High Very High
Synovitis 8 89.04 High High
Arthritis 10 75.52 Quite High
Rheumatoid Arthritis 110 73.76 Quite High
Nicotine Addiction 24 63.84 Quite High
Disease 46 8.44 Low Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Pulmonary Fibrosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This modified trimeric SP-D variant would subsequently initiate a pro-inflammatory response via calreticulin/CD91 receptor interaction and activate p38 MAPK [48].
calreticulin Binding (interaction) of CD91 associated with inflammatory response
1) Confidence 0.39 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888186 Disease Relevance 0.95 Pain Relevance 0.37
This modified trimeric SP-D variant would subsequently initiate a pro-inflammatory response via calreticulin/CD91 receptor interaction and activate p38 MAPK [48].
calreticulin Binding (interaction) of CD91 associated with inflammatory response
2) Confidence 0.39 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888186 Disease Relevance 0.95 Pain Relevance 0.37

General Comments

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