INT316676

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SFTPD) extracellular region (SFTPD) nucleus (CRX)
lysosome (SFTPD)
Anatomy Link Frequency
macrophages 1
CRX (Homo sapiens)
SFTPD (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 16 98.68 Very High Very High Very High
Inflammatory response 2 83.52 Quite High
rheumatoid arthritis 55 67.36 Quite High
methotrexate 9 5.00 Very Low Very Low Very Low
visual analogue scale 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 13 98.68 Very High Very High Very High
Rheumatoid Arthritis 55 67.36 Quite High
Arthritis 5 52.72 Quite High
Synovitis 4 42.88 Quite Low
Disease 23 31.64 Quite Low
Apoptosis 2 24.08 Low Low
Nicotine Addiction 12 17.68 Low Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Pulmonary Fibrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the absence of microbial ligands and cell debris, binding of SP-D to macrophages by the CRD region was suggested to be anti-inflammatory by blocking p38 mitogen-activated protein kinases (p38 MAPK) [47].
CRD Binding (binding) of SP-D in macrophages associated with inflammation
1) Confidence 0.05 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888186 Disease Relevance 0.65 Pain Relevance 0.33

General Comments

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