INT316765

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Context Info
Confidence 0.32
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.95
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (Hsp90b1) protein folding (Hsp90b1) cytosol (Hsp90b1)
endoplasmic reticulum (Hsp90b1) RNA binding (Hsp90b1) response to stress (Hsp90b1)
Anatomy Link Frequency
muscle fibers 2
Hsp90b1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory stimuli 3 98.20 Very High Very High Very High
Inflammation 35 87.72 High High
cytokine 2 82.84 Quite High
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 29 98.20 Very High Very High Very High
Stress 28 95.60 Very High Very High Very High
Myositis 42 80.84 Quite High
Muscle Disease 1 39.88 Quite Low
Muscular Dystrophy 1 33.32 Quite Low
Apoptosis 1 26.28 Quite Low
Aging 1 10.20 Low Low
Disease 6 5.00 Very Low Very Low Very Low
Muscle Weakness 4 5.00 Very Low Very Low Very Low
Sprains And Strains 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, a single LPS injection increased significantly Grp75 protein levels in skeletal muscle fibers, in the absence of both Grp94 [24] and MHC-I upregulation (present manuscript), proving that systemic inflammatory stimuli do raise the expression of this antioxidant stress-protein in muscle fibers.
Regulation (absence) of Localization (upregulation) of Grp94 in muscle fibers associated with stress and inflammatory stimuli
1) Confidence 0.32 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888201 Disease Relevance 0.95 Pain Relevance 0.25

General Comments

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