INT316825

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Context Info
Confidence 0.56
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.14
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ctgf, Sparc) extracellular region (Ctgf, Sparc) proteinaceous extracellular matrix (Ctgf, Sparc)
cell differentiation (Ctgf) Golgi apparatus (Ctgf) intracellular (Sparc)
Anatomy Link Frequency
fibroblasts 2
Ctgf (Mus musculus)
Sparc (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 66 50.00 Quite Low
Inflammation 18 43.04 Quite Low
corticosteroid 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Inflammatory marker 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosis 106 69.72 Quite High
INFLAMMATION 22 43.04 Quite Low
Obesity 4 28.56 Quite Low
Systemic Sclerosis 20 5.00 Very Low Very Low Very Low
Pulmonary Fibrosis 16 5.00 Very Low Very Low Very Low
Disease 16 5.00 Very Low Very Low Very Low
Targeted Disruption 12 5.00 Very Low Very Low Very Low
Keloid Scars 4 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Pulmonary Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Seventy-two hours after SPARC siRNA or Ctgf siRNA transfection, significant reductions of SPARC (95%) by SPARC siRNA and Ctgf (64%) by Ctgf siRNA were observed in the fibroblasts (Figure 2A).
Ctgf siRNA Negative_regulation (reductions) of SPARC in fibroblasts
1) Confidence 0.56 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888211 Disease Relevance 0.07 Pain Relevance 0
Seventy-two hours after SPARC siRNA or Ctgf siRNA transfection, significant reductions of SPARC (95%) by SPARC siRNA and Ctgf (64%) by Ctgf siRNA were observed in the fibroblasts (Figure 2A).
Ctgf Negative_regulation (reductions) of SPARC in fibroblasts
2) Confidence 0.49 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888211 Disease Relevance 0.07 Pain Relevance 0

General Comments

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