INT316829

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Context Info
Confidence 0.54
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 3.31
Pain Relevance 3.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (SYNM) cytoplasm (SYNM)
SYNM (Homo sapiens)
Pain Link Frequency Relevance Heat
Lasting pain 10 99.52 Very High Very High Very High
Pain 114 99.00 Very High Very High Very High
Acute pain 2 98.04 Very High Very High Very High
Fibrositis 74 94.08 High High
Chronic low back pain 6 86.80 High High
electroacupuncture 160 73.20 Quite High
imagery 30 72.04 Quite High
Anterior cingulate cortex 12 63.64 Quite High
Gabapentin 48 62.96 Quite High
Central nervous system 24 61.84 Quite High
Disease Link Frequency Relevance Heat
Pain 130 99.52 Very High Very High Very High
Cognitive Disorder 9 97.12 Very High Very High Very High
Sleep Disorders 74 94.08 High High
Low Back Pain 6 86.16 High High
Urological Neuroanatomy 84 77.24 Quite High
Neuropathic Pain 6 54.96 Quite High
Depression 8 50.68 Quite High
Handedness 1 39.20 Quite Low
Myofascial Pain Syndromes 2 34.80 Quite Low
Increased Venous Pressure Under Development 1 29.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
But it has to be mentioned that sleep, in which the young children have to be imaged, there is also reduced DMN activity (Horowitz et al., 2009).
Negative_regulation (reduced) of DMN
1) Confidence 0.54 Published 2010 Journal Frontiers in Systems Neuroscience Section Body Doc Link PMC2955419 Disease Relevance 0 Pain Relevance 0
Furthermore, perception of somatosensory stimuli near sensory threshold is facilitated by decreased DMN activity in a brief pre-event resting period [9].
Negative_regulation (decreased) of DMN
2) Confidence 0.49 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888218 Disease Relevance 0.78 Pain Relevance 0.84
Acute pain [15] is known to induce deactivation in DMN regions, whereas chronic pain may be associated with disruption of the DMN [16].
Negative_regulation (disruption) of DMN associated with lasting pain and acute pain
3) Confidence 0.49 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888218 Disease Relevance 0.81 Pain Relevance 0.74
Other studies show that activity in the DMN decreases in response to repeated painful stimuli [85], and chronic pain patients seem to exhibit permanently altered DMN activity.
Negative_regulation (decreases) of DMN associated with pain and lasting pain
4) Confidence 0.24 Published 2010 Journal Mol Pain Section Body Doc Link PMC2993660 Disease Relevance 0.85 Pain Relevance 0.80
DMN activity has been shown to decrease in relation to task-evoked activity, and demonstrates an inverse relationship with the cognitive work load of the task [81-83].
Negative_regulation (decrease) of DMN associated with cognitive disorder
5) Confidence 0.17 Published 2010 Journal Mol Pain Section Body Doc Link PMC2993660 Disease Relevance 0.87 Pain Relevance 0.94

General Comments

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