INT316831

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CCL5, MMP2) extracellular region (CCL5, MMP2) aging (CCL5)
cell-cell signaling (CCL5) cytoplasm (CCL5) peptidase activity (MMP2)
CCL5 (Homo sapiens)
MMP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 2 96.68 Very High Very High Very High
rheumatoid arthritis 40 92.16 High High
chemokine 7 81.36 Quite High
Arthritis 27 76.76 Quite High
cytokine 6 63.76 Quite High
metalloproteinase 6 52.32 Quite High
Inflammation 11 43.48 Quite Low
Osteoarthritis 21 5.00 Very Low Very Low Very Low
Bioavailability 9 5.00 Very Low Very Low Very Low
methotrexate 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 40 92.16 High High
Arthritis 33 76.76 Quite High
INFLAMMATION 17 43.48 Quite Low
Hypercalcemia 6 31.84 Quite Low
Osteoporosis 7 13.48 Low Low
Osteoarthritis 21 5.00 Very Low Very Low Very Low
Apoptosis 17 5.00 Very Low Very Low Very Low
Disease 9 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Arthropathy 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One step further, we found that EGCG significantly inhibited MMP-2 activity induced by RANTES/CCL5, Gro-?
RANTES Positive_regulation (induced) of Gene_expression (activity) of MMP-2
1) Confidence 0.02 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888220 Disease Relevance 0.51 Pain Relevance 0.59

General Comments

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