INT316886

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.86
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cd22) plasma membrane (Cd22)
Anatomy Link Frequency
B cells 2
Cd22 (Mus musculus)
Cr2 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 48 97.44 Very High Very High Very High
Arthritis 8 94.44 High High
Inflammation 4 73.44 Quite High
spastic colon 1 66.56 Quite High
Adalimumab 8 62.00 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Rheumatism 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 48 97.44 Very High Very High Very High
Arthritis 8 94.44 High High
Disease Progression 1 88.88 High High
INFLAMMATION 4 73.44 Quite High
Disease 8 72.40 Quite High
Systemic Lupus Erythematosus 11 70.96 Quite High
Systemic Sclerosis 1 69.92 Quite High
Asthma 1 67.92 Quite High
Functional Bowel Disorder 1 66.56 Quite High
Necrosis 5 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CD86 is upregulated on activated B cells upon B-cell receptor (BCR) and CD19/CD21 complex engagement [24,25].
Positive_regulation (upregulated) of B-cell receptor in B cells Binding (engagement) of CD21 in B-cell
1) Confidence 0.02 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888223 Disease Relevance 0.86 Pain Relevance 0.31

General Comments

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