INT317008

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

chromosome (OBFC1) nucleus (OBFC1) DNA binding (OBFC1)
Anatomy Link Frequency
brain 2
OBFC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
positron emission tomography 19 86.84 High High
imagery 11 78.84 Quite High
Serotonin 3 50.00 Quite Low
drug abuse 4 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cocaine 1 5.00 Very Low Very Low Very Low
opiate 1 5.00 Very Low Very Low Very Low
amygdala 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aggression 68 84.72 Quite High
Cognitive Disorder 3 65.92 Quite High
Attention Deficit Hyperactivity Disorder 15 43.52 Quite Low
Borderline Personality 1 11.68 Low Low
Bronchopulmonary Dysplasia 1 9.04 Low Low
Intellectual Impairment 9 5.00 Very Low Very Low Very Low
Drug Dependence 4 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Head Trauma 2 5.00 Very Low Very Low Very Low
Severe Combined Immunodeficiency 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We recently reported that polymorphic variants in the TPH2 gene (rs4641527; rs2129575; rs1023990; rs6582071), responsible for human brain synthesis, predicted subtle variations in 5-HT synthesis in the OBFC in a mixed sample of healthy volunteers and patients [57].
Negative_regulation (predicted) of Gene_expression (synthesis) of OBFC in brain
1) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2889822 Disease Relevance 0.27 Pain Relevance 0.26

General Comments

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