INT317009

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Context Info
Confidence 0.38
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.36
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TPH2) small molecule metabolic process (TPH2) cellular nitrogen compound metabolic process (TPH2)
response to stress (TPH2)
Anatomy Link Frequency
brain 2
TPH2 (Homo sapiens)
Pain Link Frequency Relevance Heat
positron emission tomography 19 81.68 Quite High
imagery 11 73.68 Quite High
Serotonin 3 50.00 Quite Low
drug abuse 4 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cocaine 1 5.00 Very Low Very Low Very Low
opiate 1 5.00 Very Low Very Low Very Low
amygdala 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aggression 68 96.80 Very High Very High Very High
Cognitive Disorder 3 74.80 Quite High
Attention Deficit Hyperactivity Disorder 15 52.40 Quite High
Borderline Personality 1 20.56 Low Low
Bronchopulmonary Dysplasia 1 17.92 Low Low
Intellectual Impairment 9 5.00 Very Low Very Low Very Low
Drug Dependence 4 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Head Trauma 2 5.00 Very Low Very Low Very Low
Severe Combined Immunodeficiency 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In order to control for the influence of these TPH2 polymorphisms on brain 5-HT synthesis when comparing the high and low physical aggression groups, differences in genotype distribution for each of these TPH2 variants between the trajectories were investigated.
Spec (investigated) Regulation (control) of Regulation (influence) of TPH2 in brain associated with aggression
1) Confidence 0.38 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2889822 Disease Relevance 0.36 Pain Relevance 0.24

General Comments

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