INT317033

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Context Info
Confidence 0.33
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.25
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Caml) nucleus (Tmub1) cytoplasm (Tmub1)
Anatomy Link Frequency
neuronal 1
Caml (Mus musculus)
Tmub1 (Mus musculus)
Pain Link Frequency Relevance Heat
Eae 46 98.12 Very High Very High Very High
Thalamus 10 91.12 High High
Glutamate receptor 2 90.96 High High
gABA 4 90.00 High High
Glutamate 2 78.56 Quite High
Buprenorphine 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
analgesia 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 22 81.92 Quite High
Sprains And Strains 4 5.00 Very Low Very Low Very Low
Anxiety Disorder 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Fever 2 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The interaction of Tmub1 and CAMLG was confirmed by co-immunoprecipitation assays in HEK cells.
CAMLG Binding (interaction) of Tmub1
1) Confidence 0.33 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2889838 Disease Relevance 0.19 Pain Relevance 0.18
In conclusion our study reveals that Tmub1 directly binds to CAMLG protein and the physiological function of Tmub1 is in locomotor activity and wakefulness, likely via its molecular function in thalamic neuronal circuits.


CAMLG protein Binding (binds) of Tmub1 in neuronal associated with eae
2) Confidence 0.33 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2889838 Disease Relevance 0.06 Pain Relevance 0.26

General Comments

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