INT317034

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.11
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GRIP1) endoplasmic reticulum (GRIP1) nucleus (Tmub1)
cytoplasmic membrane-bounded vesicle (GRIP1) plasma membrane (GRIP1) intracellular (GRIP1)
GRIP1 (Homo sapiens)
Tmub1 (Mus musculus)
Pain Link Frequency Relevance Heat
Thalamus 10 81.52 Quite High
Eae 46 57.92 Quite High
gABA 4 30.56 Quite Low
Glutamate 2 20.32 Low Low
Buprenorphine 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
analgesia 2 5.00 Very Low Very Low Very Low
Glutamate receptor 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 22 55.44 Quite High
Attention Deficit Hyperactivity Disorder 2 53.76 Quite High
Sprains And Strains 4 5.00 Very Low Very Low Very Low
Anxiety Disorder 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Fever 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is possible that the interaction of Tmub1 with GluR2-GRIP is indirect and requires another mediator.
GRIP Binding (interaction) of Tmub1
1) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2889838 Disease Relevance 0.06 Pain Relevance 0.10
They observed an interaction of Tmub1 and GRIP in HEK293 cells, but not in a yeast two-hybrid assay.
GRIP Neg (not) Binding (interaction) of Tmub1
2) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2889838 Disease Relevance 0.05 Pain Relevance 0.13

General Comments

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