INT31706

Context Info Confidence 0.01 First Reported 1988 Last Reported 1988 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.43

plasma membrane (Oprd1, Slc3a1) transport (Slc3a1) carbohydrate metabolic process (Slc3a1) cytoplasm (Oprd1) signal transducer activity (Oprd1)

Anatomy Link Frequency brain 1 Oprd1 (Rattus norvegicus) Slc3a1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat opioid receptor 2 100.00 Enkephalin 5 99.68 Opioid 1 83.92 Kappa opioid receptor 2 78.96 opiate 1 33.44 agonist 1 29.52

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Conditions for the equilibrium binding to opioid receptor of [3H]sufentanil (mu selective), [3H][D-Pen2,D-Pen5]enkephalin (delta selective), and [3H]U69,593 (kappa selective) were established in membranes from rat brain cerebrum, monkey cortex, or guinea pig cerebellum.

opioid receptor Binding (binding) of D-Pen2 in brain associated with enkephalin and opioid receptor

1) Confidence 0.01 Published 1988 Journal Eur. J. Pharmacol. Section Abstract Doc Link 2898375 Disease Relevance 0 Pain Relevance 0.43

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